What is the note on the 2nd fret of the 6th (low E) string?

The note on the 2nd fret of the 6th (low E) string is F#. On a standard-tuned guitar, the E string is the lowest string, which is tuned to the note E. When you press down on the 2nd fret of this string, you raise the pitch by a whole step, leading to the note F#.

To break it down, the first fret of the E string raises the note to F, and moving up to the 2nd fret raises it one half step further to F#. Understanding the layout of the guitar fretboard and the corresponding notes on each fret allows for better navigation and proficiency in playing.

This knowledge is fundamental for musicians as it is the basis for constructing scales, playing chords, and improvisational soloing. F# is commonly used in various musical contexts, thus familiarity with its position on the fretboard is essential for any guitarist.