What note is located at the 1st fret of the 1st string?

The note located at the 1st fret of the 1st string (high E string) is F. In standard tuning, the 1st string is tuned to E. When you press down on the 1st fret, you are raising the pitch of that open string by one half step, which brings it to F.

Understanding the layout of the fretboard in relation to musical notes is crucial for mastering guitar. Each fret represents one semitone (or half step), meaning that moving from one fret to the next raises the pitch by that same interval. Starting from E at the open string and moving to the 1st fret gives you F, highlighting the concept of half steps on the guitar neck.