Which note corresponds to the 2nd fret of the E string?

The note that corresponds to the 2nd fret of the E string is F#. When tuning a standard guitar, the open E string is the note E. Moving up the fretboard, each fret represents a half-step increase in pitch.

Hence, the first fret on the E string is an F note, and the second fret is one half-step higher, resulting in F#. This is fundamental to understanding how the fretboard is laid out, as the E string starts with E at the open string, followed by F at the first fret, and then F# at the second.

Knowing the relationship between the notes on the fretboard is crucial for playing scales, constructing chords, and improvisation, as it helps guitarists navigate the instrument efficiently.